Overview
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.7
USERS' SCORE
Good
Based on 3 Reviews
8
Supplement Facts
Serving Size: 2 Veg Capsules
Serving Per Container: 60
Amount Per Serving
%DV
BioCell Collagen® (Hydrolyzed Chicken Sternal Cartilage Extract) providing
1 g (1,000 mg)
**
Hydrolyzed Type II Collagen
570 mg
**
Chondroitin Sulfate
190 mg
**
Hyaluronic Acid
95 mg
**
Top Medical Research Studies
9
We conducted a study to explore whether intraarticular injections of hyaluronic acid (HA) could effectively treat chronic, nonradicular low back pain as compared to glucocorticoids. Sixty patients participated in a well-structured clinical trial where they received either HA or glucocorticoid injections.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Read More
9
We examined how cross-linked hyaluronic acid (cHA) hydrogel can help reduce epidural fibrosis after back surgeries, which is a common cause of ongoing pain. In our study with rat models, we compared groups that received cHA to those that did not.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
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2
We assessed the effectiveness of hyaluronic acid (HA) injections for lumbar facet joint arthritis in a small pilot study involving thirteen patients. Each participant underwent a thorough evaluation before treatment, using questionnaires to gauge pain levels and disability. After a precise HA injection, we followed up with evaluations six weeks later.
Unfortunately, our findings indicated that there was no significant improvement in back pain or symptoms following the treatment. This suggests that HA may not be effective for managing lumbar facet joint arthritis at this stage.
Unfortunately, our findings indicated that there was no significant improvement in back pain or symptoms following the treatment. This suggests that HA may not be effective for managing lumbar facet joint arthritis at this stage.
Read More
Most Useful Reviews
7
Knee pain relief
9 people found this helpful
After years of knee pain, I took one collagen capsule and noticed a dramatic improvement within 24 hours. My knee pain has almost vanished, and notably, my back pain feels better too. I am genuinely thrilled with these results!
Read More
9
Significant improvement
This is a good preparation for joints. I purchased it for my mother, who is 70 years old and suffers from knee osteoarthritis along with back pain. She combines it with MSM and omega-3 during her breaks from hydroprotectors. The improvement has been quite noticeable; she reported that her back pain and discomfort in one knee have almost entirely disappeared, and there has been a noticeable reduction in the second knee. Her overall health has significantly improved since starting this treatment, and I am very satisfied with the results.
Read More
6
Joint pain alleviation
47 people found this helpful
I initially purchased this product for my hair concerns, but it unexpectedly helped with joint pain as well. I've noticed a notable reduction in discomfort from old injuries while working out. This supplement has proven highly effective for my overall health.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.7
- All Researches
9
Collagen supplements provide pain relief
We examined the impact of collagen supplements combined with therapeutic exercise on chronic low back pain. In this study, sixty participants were divided into two groups—one receiving only exercise and another incorporating a blend of food supplements alongside their exercises.
The results showed that those who used the collagen supplements saw significant pain relief and better overall functionality compared to those who didn't. This suggests that combining exercise with collagen supplementation can be an effective approach for managing chronic back pain.
The results showed that those who used the collagen supplements saw significant pain relief and better overall functionality compared to those who didn't. This suggests that combining exercise with collagen supplementation can be an effective approach for managing chronic back pain.
Read More
9
We examined how cross-linked hyaluronic acid (cHA) hydrogel can help reduce epidural fibrosis after back surgeries, which is a common cause of ongoing pain. In our study with rat models, we compared groups that received cHA to those that did not.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
Read More
9
We conducted a study to explore whether intraarticular injections of hyaluronic acid (HA) could effectively treat chronic, nonradicular low back pain as compared to glucocorticoids. Sixty patients participated in a well-structured clinical trial where they received either HA or glucocorticoid injections.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Read More
8
We examined the effects of hyaluronic acid in healing back pain linked to disc degeneration. In our study, New Zealand white rabbits undergoing a partial nucleotomy received either PGA/HA implants or bioactivated fibrin, while controls underwent the procedure without any treatment.
Our results indicated that the use of PGA/HA implants led to more effective tissue repair, evidenced by a significant increase in type II collagen content, compared to the untreated controls. However, there was no change in the water content of the discs over the six-month period, highlighting that while tissue repair may improve, it may not directly enhance disc hydration or overall disc function.
Our results indicated that the use of PGA/HA implants led to more effective tissue repair, evidenced by a significant increase in type II collagen content, compared to the untreated controls. However, there was no change in the water content of the discs over the six-month period, highlighting that while tissue repair may improve, it may not directly enhance disc hydration or overall disc function.
Read More
8
Sacroiliac joint pain treatment review
We explored the complex nature of chronic pain in the sacroiliac joint, which has long sparked debate due to its anatomical position. This makes accurate diagnosis challenging, often requiring advanced techniques like guided injections.
While there are various treatment options available for sacroiliac joint syndrome, no single method has proven to be ideal. However, using hyaluronic acid through intra-articular viscosupplementation has shown promise in delivering long-lasting pain relief, promoting healthy joint function, and enhancing synovial fluid properties.
While there are various treatment options available for sacroiliac joint syndrome, no single method has proven to be ideal. However, using hyaluronic acid through intra-articular viscosupplementation has shown promise in delivering long-lasting pain relief, promoting healthy joint function, and enhancing synovial fluid properties.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
7
Knee pain relief
9 people found this helpful
After years of knee pain, I took one collagen capsule and noticed a dramatic improvement within 24 hours. My knee pain has almost vanished, and notably, my back pain feels better too. I am genuinely thrilled with these results!
Read More
9
Significant improvement
This is a good preparation for joints. I purchased it for my mother, who is 70 years old and suffers from knee osteoarthritis along with back pain. She combines it with MSM and omega-3 during her breaks from hydroprotectors. The improvement has been quite noticeable; she reported that her back pain and discomfort in one knee have almost entirely disappeared, and there has been a noticeable reduction in the second knee. Her overall health has significantly improved since starting this treatment, and I am very satisfied with the results.
Read More
6
Joint pain alleviation
47 people found this helpful
I initially purchased this product for my hair concerns, but it unexpectedly helped with joint pain as well. I've noticed a notable reduction in discomfort from old injuries while working out. This supplement has proven highly effective for my overall health.
Read More
Frequently Asked Questions
9
Significant improvement
This is a good preparation for joints. I purchased it for my mother, who is 70 years old and suffers from knee osteoarthritis along with back pain. She combines it with MSM and omega-3 during her breaks from hydroprotectors. The improvement has been quite noticeable; she reported that her back pain and discomfort in one knee have almost entirely disappeared, and there has been a noticeable reduction in the second knee. Her overall health has significantly improved since starting this treatment, and I am very satisfied with the results.
7
We examined the effects of Cartilox, a supplement containing hydrolyzed type II collagen, hyaluronic acid, and other ingredients, on back pain and osteoarthritis. In a clinical study with 60 participants, half were given the supplement alongside physical therapy while the other half only received physical therapy.
After a month, those taking Cartilox showed improvements in pain levels without significant side effects or changes in health indicators. These findings suggest that Cartilox could be a helpful option for individuals with mild pain from back issues and osteoarthritis.
After a month, those taking Cartilox showed improvements in pain levels without significant side effects or changes in health indicators. These findings suggest that Cartilox could be a helpful option for individuals with mild pain from back issues and osteoarthritis.
9
Collagen supplements provide pain relief
We examined the impact of collagen supplements combined with therapeutic exercise on chronic low back pain. In this study, sixty participants were divided into two groups—one receiving only exercise and another incorporating a blend of food supplements alongside their exercises.
The results showed that those who used the collagen supplements saw significant pain relief and better overall functionality compared to those who didn't. This suggests that combining exercise with collagen supplementation can be an effective approach for managing chronic back pain.
The results showed that those who used the collagen supplements saw significant pain relief and better overall functionality compared to those who didn't. This suggests that combining exercise with collagen supplementation can be an effective approach for managing chronic back pain.
4
We examined the effectiveness of hyaluronic acid in managing chronic low back pain originating from facet joint osteoarthritis. Our systematic review analyzed various injectable treatments, focusing on outcomes from randomized clinical trials.
While steroids and local anesthetics showed promising results, hyaluronic acid did not demonstrate significant benefits, unlike other treatments we explored.
Overall, injections for this type of back pain are encouraging, especially with medial branch blocks, but the role of hyaluronic acid remains unclear.
While steroids and local anesthetics showed promising results, hyaluronic acid did not demonstrate significant benefits, unlike other treatments we explored.
Overall, injections for this type of back pain are encouraging, especially with medial branch blocks, but the role of hyaluronic acid remains unclear.
References
- Shavlovskaya OA. [Complex effects of physical exertion with dietary supplements Cartilox in pain syndrome effectiveness and safety evaluation]. Vopr Kurortol Fizioter Lech Fiz Kult. 2022;99:20. doi:10.17116/kurort20229904120
- Farì G, Santagati D, Pignatelli G, Scacco V, Renna D, et al. Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain. Endocr Metab Immune Disord Drug Targets. 2022;22:108. doi:10.2174/1871530321666210210153619
- Lee DH, Park KS, Shin HE, Kim SB, Choi H, et al. Safety and Feasibility of Intradiscal Administration of Matrilin-3-Primed Adipose-Derived Mesenchymal Stromal Cell Spheroids for Chronic Discogenic Low Back Pain: Phase 1 Clinical Trial. Int J Mol Sci. 2023;24. doi:10.3390/ijms242316827
- Goode AP, Cleveland RJ, Kraus VB, Taylor KA, George SZ, et al. Biomarkers and longitudinal changes in lumbar spine degeneration and low back pain: the Johnston County Osteoarthritis Project. Osteoarthritis Cartilage. 2023;31:809. doi:10.1016/j.joca.2023.02.005
- Baroncini A, Maffulli N, Eschweiler J, Knobe M, Tingart M, et al. Management of facet joints osteoarthritis associated with chronic low back pain: A systematic review. Surgeon. 2021;19:e512. doi:10.1016/j.surge.2020.12.004
- Amirdelfan K, Bae H, McJunkin T, DePalma M, Kim K, et al. Allogeneic mesenchymal precursor cells treatment for chronic low back pain associated with degenerative disc disease: a prospective randomized, placebo-controlled 36-month study of safety and efficacy. Spine J. 2021;21:212. doi:10.1016/j.spinee.2020.10.004
- Annaswamy TM, Armstead C, Carlson L, Elkins NJ, Kocak D, et al. Intra-articular Triamcinolone Versus Hyaluronate Injections for Low Back Pain With Symptoms Suggestive of Lumbar Zygapophyseal Joint Arthropathy: A Pragmatic, Double-Blind Randomized Controlled Trial. Am J Phys Med Rehabil. 2018;97:278. doi:10.1097/PHM.0000000000000879
- Kumar H, Ha DH, Lee EJ, Park JH, Shim JH, et al. Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study. Stem Cell Res Ther. 2017;8:262. doi:10.1186/s13287-017-0710-3
- Wu CY, Huang YH, Lee JS, Tai TW, Wu PT, et al. Efficacy of topical cross-linked hyaluronic acid hydrogel in preventing post laminectomy/laminotomy fibrosis in a rat model. J Orthop Res. 2016;34:299. doi:10.1002/jor.23001
- Endres M, Zenclussen ML, Casalis PA, Freymann U, Gil Garcia S, et al. Augmentation and repair tissue formation of the nucleus pulposus after partial nucleotomy in a rabbit model. Tissue Cell. 2014;46:505. doi:10.1016/j.tice.2014.09.003
- Cleary M, Keating C, Poynton AR. Viscosupplementation in lumbar facet joint arthropathy: a pilot study. J Spinal Disord Tech. 2008;21:29. doi:10.1097/BSD.0b013e318057720c
- Fuchs S, Erbe T, Fischer HL, Tibesku CO. Intraarticular hyaluronic acid versus glucocorticoid injections for nonradicular pain in the lumbar spine. J Vasc Interv Radiol. 2005;16:1493.
- Calvillo O, Skaribas I, Turnipseed J. Anatomy and pathophysiology of the sacroiliac joint. Curr Rev Pain. 2000;4:356.
- Srejic U, Calvillo O, Kabakibou K. Viscosupplementation: a new concept in the treatment of sacroiliac joint syndrome: a preliminary report of four cases. Reg Anesth Pain Med. 1999;24:84.
